IL23A antibody

Volume : 100 µg
Purification : Protein A+G purification
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Mouse
Clonality : monoclonal
Clone ID : 2G1
Isotype : IgG1
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background : Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stim µLates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
Immunogen : interleukin 23, alpha subunit p19
Aliases : IL 23, IL 23 A, IL 23 subunit alpha, IL 23A, IL 23p19, IL23A, IL23P19, Interleukin 23 subunit alpha, Interleukin 23 subunit p19, P19, SGRF
Observed MW : 21 kDa
Uniprot ID : Q9NPF7
Reactivity : Human
Application : ELISA, WB, IHC
Recommended dilution : WB : 1 : 500-1 : 2000; IHC : 1 : 20-1 : 200
Gene ID : 51561
Research Area : Immunology, Signal Transduction, Developmental biology