GEMIN7 antibody

Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background : The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins(snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cell µLar pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1 SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1 SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus.
Immunogen : gem(nuclear organelle) associated protein 7
Aliases :
Observed MW :
Uniprot ID : Q9H840
Reactivity : Human, Mouse, Rat
Application : ELISA
Recommended dilution :
Gene ID : 79760
Research Area : Neuroscience