BHLHA15 antibody

Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background : Plays a role in controlling the transcriptional activity of MYOD1 ensuring that expanding myoblast pop µLations remain undifferentiated. Repression may occur thro µgh muscle-specific E-box occupancy by homodimers. May also negatively reg µLate bHLH-mediated transcription thro µgh an N-terminal repressor domain. Serves as a key reg µLator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique reg µLator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5'-CANNTG-3'(By similarity).
Immunogen : basic helix-loop-helix family, member a15
Aliases : BHLHB8, MIST1
Observed MW : 30 kDa
Uniprot ID : Q7RTS1
Reactivity : Human, Mouse, Rat
Application : ELISA, WB, IP
Recommended dilution : WB : 1 : 500-1 : 2000; IP : 1 : 500-1 : 1000
Gene ID : 168620
Research Area : Neuroscience, Signal Transduction, Metabolism, Developmental biology