BAX antibody

Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 12 months (Avoid repeated freeze / thaw cycles.)
Background : The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic reg µLators that are involved in a wide variety of cell µLar activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is reg µLated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. M µLtiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene.
Immunogen : BCL2-associated X protein
Aliases : BCL2L4, Apoptosis reg µLator BAX, BAX
Observed MW : 21 kDa
Uniprot ID : Q07812
Reactivity : Human, Mouse, Rat
Application : ELISA, WB, IHC, IF
Recommended dilution : WB : 1 : 500 - 1 : 2000; IHC : 1 : 50 - 1 : 100; IF : 1 : 50 - 1 : 200
Gene ID : 581
Research Area : Neuroscience, Cancer, Developmental biology