FOXO4 (Ab 197) Antibody

Volume : 100 µL
Clone Number :
Aliases : AFX antibody; AFX1 antibody; Afxh antibody; ALL1-fused gene from X chromosome antibody; Fork head domain transcription factor AFX1 antibody; Forkhead box O4 antibody; Forkhead box protein O4 antibody; FOXO 4 antibody; Foxo4 antibody; FOXO4_HUMAN antibody; MGC117660 antibody; MGC120490 antibody; Mixed lineage leukemia; translocated to; 7 antibody; MLLT7 antibody; Myeloid/lymphoid or mixed lineage leukemia (trithorax homolog; Drosophila); translocated to; 7 antibody; Myeloid/lymphoid or mixed lineage leukemia; translocated to; 7 antibody; RGD1561201 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P98177
Immunogen : Peptide sequence around aa. 195~199 (A-A-S-M-D) derived from Human AFX.
Raised in : Rabbit
Species Reactivity : Human, Mouse, Rat
Tested Applications : ELISA, WB, IHC; WB : 1 : 500-1 : 1000, IHC : 1 : 50-1 : 200
Background : Transcription factor involved in the reg µLation of the ins µLin signaling pathway. Binds to ins µLin-response elements (IREs) and can activate transcription of IGFBP1. Down-reg µLates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-mod µLated genes. Also involved in negative reg µLation of the cell cycle.

Di Maira G, et al. (2005)Cell Death Differ; 12(6) : 668-77.
Essers MA, et al. EMBO J 2004 Nov. 11.
Brownawell AM, (2001) Mol Cell Biol; 21(10) : 3534-46.
Kops GJ, et al. (1999) Nature; 398(6728) : 630-4.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conj µgates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Conj µgate : Non-conj µgated
Buffer : Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FOXO4
Research Areas : Epigenetics and Nuclear Signaling