ANKRD28 Antibody

Volume : 50 µL
Clone Number :
Aliases : ANKRD28 antibody; KIAA0379Serine/threonine-protein phosphatase 6 reg µLatory ankyrin repeat subunit A antibody; PP6-ARS-A antibody; Serine/threonine-protein phosphatase 6 reg µLatory subunit ARS-A antibody; Ankyrin repeat domain-containing protein 28 antibody; Phosphatase interactor targeting protein hnRNP K antibody; PITK antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O15084
Immunogen : Synthetic peptide of Human ANKRD28
Raised in : Rabbit
Species Reactivity : Human, Mouse
Tested Applications : ELISA, WB; ELISA : 1 : 1000-1 : 2000, WB : 1 : 200-1 : 1000
Background : Putative reg µLatory subunit of protein phosphatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates. Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha. Selectively inhibits the phosphatase activity of PPP1C. Targets PPP1C to mod µLate HNRPK phosphorylation. ANKRD28 selectively reg µLated phosphorylation of hnRNP-K at ser284, an effect that was enhanced in vivo by an S1013A/S1017A double mutant, s µggesting that ANKRD28 targets PP1 in a reg µLated manner to dephosphorylate hnRNP-K selectively at ser284.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen affinity purification
Conj µgate : Non-conj µgated
Buffer : -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ANKRD28
Research Areas : Epigenetics and Nuclear Signaling;Cell biology;Signal transduction