INPP5F Antibody FITC conjugated

Volume : 50 µL
Clone Number :
Aliases : INPP5F antibody; KIAA0966 antibody; SAC2 antibody; MSTP007 antibody; MSTP047 antibody; Phosphatidylinositide phosphatase SAC2 antibody; EC 3.1.3.25 antibody; Inositol polyphosphate 5-phosphatase F antibody; Sac domain-containing inositol phosphatase 2 antibody; Sac domain-containing phosphoinositide 4-phosphatase 2 antibody; hSAC2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9Y2H2
Immunogen : Peptide sequence from Human Phosphatidylinositide phosphatase SAC2 protein (187-204AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Inositol 4-phosphatase which mainly acts on phosphatidylinositol 4-phosphate. May be functionally linked to OCRL, which converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol, for a sequential dephosphorylation of phosphatidylinositol 4,5-bisphosphate at the 5 and 4 position of inositol, thus playing an important role in the endocytic recycling (PubMed : 25869669). Reg µLator of TF : TFRC and integrins recycling pathway, is also involved in cell migration mechanisms (PubMed : 25869669). Mod µLates AKT/GSK3B pathway by decreasing AKT and GSK3B phosphorylation (PubMed : 17322895). Negatively reg µLates STAT3 signaling pathway thro µgh inhibition of STAT3 phosphorylation and translocation to the nucleus (PubMed : 25476455). Functionally important mod µLator of cardiac myocyte Volume and of the cardiac response to stress (By similarity). May play a role as negative reg µLator of axon regeneration after central nervous system injuries (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : INPP5F
Research Areas : Cancer; Metabolism; Signal transduction