INO80 Antibody Biotin conjugated

Volume : 50 µg
Clone Number :
Aliases : DNA helicase INO80 antibody; hINO80 antibody; homolog of yeast INO80 antibody; INO80 antibody; INO80 complex subunit A antibody; INO80 homolog antibody; INO80_HUMAN antibody; INO80A antibody; INOC1 antibody; KIAA1259 antibody; Putative DNA helicase INO80 complex homolog 1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9 µLG1
Immunogen : Recombinant Human Chromatin-remodeling ATPase INO80 protein (1365-1495AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : ATPase component of the chromatin remodeling INO80 complex which is involved in transcriptional reg µLation, DNA replication and DNA repair (PubMed : 16230350, PubMed : 16298340, PubMed : 17721549, PubMed : 20855601 PubMed : 20237820). Binds DNA (PubMed : 16298340, PubMed : 21303910). As part of the INO80 complex, remodels chromatin by shifting nucleosomes (PubMed : 16230350, PubMed : 21303910). Reg µLates transcription upon recruitment by YY1 to YY1-activated genes, where it acts as an essential coactivator (PubMed : 17721549). Involved in UV-damage excision DNA repair (PubMed : 20855601). The contribution to DNA double-strand break repair appears to be largely indirect thro µgh transcriptional reg µLation (PubMed : 20687897). Involved in DNA replication (PubMed : 20237820). Required for microtub µLe assembly during mitosis thereby reg µLating chromosome segregation cycle (PubMed : 20237820).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : INO80
Research Areas : Epigenetics and Nuclear Signaling