ICK Antibody HRP conjugated

Volume : 50 µg
Clone Number :
Aliases : CILK1 antibody; ICK antibody; KIAA0936Serine/threonine-protein kinase ICK antibody; EC 2.7.11.1 antibody; Ciliogenesis associated kinase 1 antibody; Intestinal cell kinase antibody; hICK antibody; Laryngeal cancer kinase 2 antibody; LCK2 antibody; MAK-related kinase antibody; MRK antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9UPZ9
Immunogen : Recombinant Human Serine/threonine-protein kinase ICK protein (150-275AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Required for ciliogenesis (PubMed : 24797473). Phosphorylates KIF3A (By similarity). Involved in the control of ciliary length (PubMed : 24853502). Reg µLates the ciliary localization of SHH pathway components as well as the localization of IFT components at ciliary tips (By similarity). May play a key role in the development of m µLtiple organ systems and partic µLarly in cardiac development (By similarity). Reg µLates intraflagellar transport (IFT) speed and negatively reg µLates cilium length in a cAMP and mTORC1 signaling-dependent manner and this reg µLation requires its kinase activity (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ICK
Research Areas : Epigenetics and Nuclear Signaling; Cell biology