BATF2 Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : BATF2Basic leucine zipper transcriptional factor ATF-like 2 antibody; B-ATF-2 antibody; Suppressor of AP-1 reg µLated by IFN antibody; SARI antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8N1L9
Immunogen : Recombinant Human Basic leucine zipper transcriptional factor ATF-like 2 protein (1-189AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : AP-1 family transcription factor that controls the differentiation of lineage-specific cells in the immune system. Following infection, participates in the differentiation of CD8(+) thymic conventional dendritic cells in the immune system. Acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5\'-TGA[CG]TCA-3\' and reg µLates expression of target genes. Selectively suppresses CYR61/CCN1 transcription and hence blocks the downstream cell proliferation signals produced by CYR61 and inhibits CYR61-induced anchorage-independent growth and invasion in several cancer types, such as breast cancer, malignant glioma and metastatic melanoma. Possibly acts by interfering with AP-1 binding to CYR61 promoter.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BATF2
Research Areas : Epigenetics and Nuclear Signaling