CAND1 Antibody HRP conjugated

Volume : 50 µg
Clone Number :
Aliases : CAND 1 antibody; Cand1 antibody; CAND1_HUMAN antibody; C µLlin associated and neddylation dissociated 1 antibody; C µLlin associated and neddylation dissociated protein 1 antibody; C µLlin associated NEDD8 dissociated protein 1 antibody; C µLlin-associated and neddylation-dissociated protein 1 antibody; C µLlin-associated NEDD8-dissociated protein 1 antibody; DKFZP434M1414 antibody; FLJ10114 antibody; FLJ10929 antibody; FLJ38691 antibody; FLJ90441 antibody; KIAA0829 antibody; p120 CAND1 antibody; TATA binding protein interacting protein 120A antibody; TBP interacting protein antibody; TBP interacting protein of 120 kDa A antibody; TBP Interacting Protein TIP120A antibody; TBP-interacting protein 120A antibody; TBP-interacting protein of 120 kDa A antibody; TIP120 antibody; TIP120 protein antibody; TIP120A antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q86VP6
Immunogen : Recombinant Human C µLlin-associated NEDD8-dissociated protein 1 protein (1150-1230AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Key assembly factor of SCF (SKP1-C µL1-F-box protein) E3 ubiquitin ligase complexes that promotes the exchange of the substrate-recognition F-box subunit in SCF complexes, thereby playing a key role in the cell µLar repertoire of SCF complexes. Acts as a F-box protein exchange factor. The exchange activity of CAND1 is coupled with cycles of neddylation conj µgation : in the deneddylated state, c µLlin-binding CAND1 binds C µL1-RBX1 increasing dissociation of the SCF complex and promoting exchange of the F-box protein. Probably plays a similar role in other c µLlin-RING E3 ubiquitin ligase complexes.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CAND1
Research Areas : Epigenetics and Nuclear Signaling