BRAP Antibody FITC conjugated

Volume : 50 µg
Clone Number :
Aliases : BRAP antibody; RNF52BRCA1-associated protein antibody; EC 2.3.2.27 antibody; BRAP2 antibody; Impedes mitogenic signal propagation antibody; IMP antibody; RING finger protein 52 antibody; RING-type E3 ubiquitin transferase BRAP2 antibody; Renal carcinoma antigen NY-REN-63 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q7Z569
Immunogen : Recombinant Human BRCA1-associated protein (13-124AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Negatively reg µLates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination res µLting in the release of inhibition of Raf/MEK complex formation. May also act as a cytoplasmic retention protein with a role in reg µLating nuclear transport.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BRAP
Research Areas : Epigenetics and Nuclear Signaling; Signal transduction