BLOC1S2 Antibody

Volume : 50 µL
Clone Number :
Aliases : Biogenesis of lysosome-related organelles complex 1 subunit 2 antibody; BL1S2_HUMAN antibody; BLOC-1 subunit 2 antibody; Bloc1s2 antibody; BLOS2 antibody; Centrosome-associated protein antibody; RP11 316M21.4 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q6QNY1
Immunogen : Recombinant Human Biogenesis of lysosome-related organelles complex 1 subunit 2 protein (44-142AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA, IHC; Recommended dilution : IHC : 1 : 20-1 : 200
Background : Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense gran µLes and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracell µLar vesicle trafficking. May play a role in cell proliferation.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen Affinity Purified
Conj µgate : Non-conj µgated
Buffer : PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BLOC1S2
Research Areas : Epigenetics and Nuclear Signaling; Signal transduction