IPO7 Antibody

Volume : 50 µL
Clone Number :
Aliases : FLJ14581 antibody; Imp 7 antibody; Imp7 antibody; Importin-7 antibody; Importin7 antibody; IPO 7 antibody; IPO7 antibody; IPO7_HUMAN antibody; MGC138673 antibody; Ran binding protein 7 antibody; Ran-binding protein 7 antibody; RANBP 7 antibody; RanBP7 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O95373
Immunogen : Synthetic peptide of Human IPO7
Raised in : Rabbit
Species Reactivity : Human, Mouse
Tested Applications : ELISA, WB, IHC; ELISA : 1 : 2000-1 : 5000, WB : 1 : 500-1 : 2000, IHC : 1 : 100-1 : 300
Background : The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. Similar to importin-beta, this protein prevents the activation of Ran's GTPase by RanGAP1 and inhibits nucleotide exchange on RanGTP, and also binds directly to nuclear pore complexes where it competes for binding sites with importin-beta and transportin. This protein has a Ran-dependent transport cycle and it can cross the nuclear envelope rapidly and in both directions. At least four importin beta-like transport receptors, namely importin beta itself, transportin, RanBP5 and RanBP7, directly bind and import ribosomal proteins.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen affinity purification
Conj µgate : Non-conj µgated
Buffer : -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IPO7
Research Areas : Epigenetics and Nuclear Signaling;Signal transduction