lasA Antibody Biotin conjugated

Volume : 50 µg
Clone Number :
Aliases : lasA antibody; PA1871Protease LasA antibody; EC 3.4.24.- antibody; Staphylolytic protease antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Pseudomonas aer µginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
UniProt ID : P14789
Immunogen : Recombinant Pseudomonas aer µginosa Protease LasA protein (237-418AA)
Raised in : Rabbit
Species Reactivity : Pseudomonas aer µginosa
Tested Applications : ELISA
Background : Involved in proteolysis and elastolysis (degradation of the host protein elastin). Has staphylolytic activity (degrades pentaglycine cross-links in cell wall peptidogylcan), preferring Gly-Gly-|-X substrates where X is Ala or Gly (PubMed : 11179971). Enhances the elastolytic but not proteolytic activity of elastase (lasB) and elastolytic activity of other proteases (PubMed : 2110137). Degradation of host elastin is likely to contribute to the pathogenicity of P.aer µginosa. While either His-317 or His-356 can abstract a proton in the hydrolysis reaction, the same residue performs both functions in a given catalytic cycle, with the other stabilizing the catalytic intermediate (PubMed : 20026068).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : lasA
Research Areas : Others