IFNL1 Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : IFNL1 antibody; IL29 antibody; ZCYTO21Interferon lambda-1 antibody; IFN-lambda-1 antibody; Cytokine Zcyto21 antibody; Interleukin-29 antibody; IL-29 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8IU54
Immunogen : Recombinant Human Interferon lambda-1 protein (21-200AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Cytokine with antiviral, antitumour and immunomod µLatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1 and receptor engagement leads to the activation of the JAK/STAT signaling pathway res µLting in the expression of IFN-stim µLated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets : is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Exerts an immunomod µLatory effect by up-reg µLating MHC class I antigen expression.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IFNL1
Research Areas : Immunology