BMI1 Antibody Biotin conjugated

Volume : 50 µg
Clone Number :
Aliases : B lymphoma Mo MLV insertion region (mouse) antibody; B lymphoma Mo MLV insertion region 1 homolog antibody; Bmi 1 antibody; BMI1 antibody; BMI1 polycomb ring finger oncogene antibody; BMI1_HUMAN antibody; Flvi 2/bmi 1 antibody; FLVI2/BMI1 antibody; MGC12685 antibody; Murine leukemia viral (bmi 1) oncogene homolog antibody; Oncogene BMI 1 antibody; PCGF 4 antibody; PCGF4 antibody; Polycomb complex protein BMI 1 antibody; Polycomb complex protein BMI-1 antibody; Polycomb group protein Bmi1 antibody; Polycomb group ring finger 4 antibody; Polycomb group RING finger protein 4 antibody; RING finger protein 51 antibody; RNF 51 antibody; RNF51 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P35226
Immunogen : Recombinant Human Polycomb complex protein BMI-1 protein (1-247AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Component of a Polycomb group (PcG) m µLtiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, thro µghout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A \\\'Lys-119\\\', rendering chromatin heritably changed in its expressibility (PubMed : 15386022, PubMed : 16359901 PubMed : 26151332, PubMed : 16714294, PubMed : 21772249, PubMed : 25355358, PubMed : 27827373). The complex composed of RNF2, UB2D3 and BMI1 binds nucleosomes, and has activity only with nucleosomal histone H2A (PubMed : 21772249, PubMed : 25355358). In the PRC1-like complex, reg µLates the E3 ubiquitin-protein ligase activity of RNF2/RING2 (PubMed : 15386022, PubMed : 26151332, PubMed : 21772249).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BMI1
Research Areas : Epigenetics and Nuclear Signaling; Cancer; Cell biology; Stem cells