Irf8 Antibody Biotin conjugated

Volume : 50 µg
Clone Number :
Aliases : Irf8 antibody; Icsbp antibody; Icsbp1 antibody; Interferon reg µLatory factor 8 antibody; IRF-8 antibody; Interferon consensus sequence-binding protein antibody; ICSBP antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Mus musc µLus (Mouse)
UniProt ID : P23611
Immunogen : Recombinant Mouse Interferon reg µLatory factor 8 protein (1-424AA)
Raised in : Rabbit
Species Reactivity : Mouse
Tested Applications : ELISA
Background : Specifically binds to the upstream reg µLatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)). Plays a reg µLatory role in cells of the immune system. Involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5\'-TGAnTCA/GAAA-3\'), an immune-specific reg µLatory element, followed by cooperative binding of BATF and IRF8 and activation of genes.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : Irf8
Research Areas : Epigenetics and Nuclear Signaling; Immunology