IGHG3 Antibody Biotin conjugated

Volume : 50 µL
Clone Number :
Aliases : IGHG3Immunoglob µLin heavy constant gamma 3 antibody; HDC antibody; Heavy chain disease protein antibody; Ig gamma-3 chain C region antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P01860
Immunogen : Peptide sequence from Human Immunoglob µLin heavy constant gamma 3 protein (312-324AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Constant region of immunoglob µLin heavy chains. Immunoglob µLins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglob µLins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglob µLins-secreting plasma cells. Secreted immunoglob µLins mediate the effector phase of humoral immunity, which res µLts in the elimination of bound antigens (PubMed : 22158414, PubMed : 20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglob µLin has two antigen binding sites with remarkable affinity for a partic µLar antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a partic µLar antigen (PubMed : 17576170, PubMed : 20176268).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IGHG3
Research Areas : Signal Transduction