GCGR Antibody HRP conjugated
Volume : 50 µg
Clone Number :
Aliases : Gcgr antibody; GGR antibody; GL R antibody; GL-R antibody; GLR antibody; GLR_HUMAN antibody; Glucagon receptor antibody; Glucagon receptor precursor antibody; MGC138246 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P47871
Immunogen : Recombinant Human Glucagon receptor protein (26-136AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : G-protein coupled receptor for glucagon that plays a central role in the reg µLation of blood glucose levels and glucose homeostasis. Reg µLates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and mod µLates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase. Besides, plays a role in signaling via a phosphatidylinositol-calcium second messenger system.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : GCGR
Research Areas : Cancer; Metabolism; Signal transduction