BMP10 Antibody HRP conjugated

Volume : 50 µg
Clone Number :
Aliases : BMP-10 antibody; Bmp10 antibody; BMP10_HUMAN antibody; Bone morphogenetic protein 10 antibody; Bone morphogenetic protein 10 preproprotein antibody; MGC126783 antibody; OTTHUMP00000159973 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O95393
Immunogen : Recombinant Human Bone morphogenetic protein 10 protein (317-424AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle reg µLator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1 BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1 SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BMP10
Research Areas : Cardiovasc µLar; Signal transduction