BCL2L1 Antibody HRP conjugated
Volume : 50 µg
Clone Number :
Aliases : Apoptosis reg µLator Bcl X antibody; Apoptosis reg µLator Bcl-X antibody; Apoptosis reg µLator BclX antibody; B cell lymphoma 2 like antibody; B2CL1_HUMAN antibody; Bcl 2 like 1 protein antibody; Bcl X antibody; Bcl xL antibody; BCL XL/S antibody; Bcl xS antibody; Bcl-2-like protein 1 antibody; Bcl2 Like 1 antibody; Bcl2 related gene antibody; Bcl2-L-1 antibody; BCL2L antibody; Bcl2l1 antibody; BCLX antibody; BclXL antibody; BclXs antibody; DKFZp781P2092 antibody; PPP1R52 antibody; Protein phosphatase 1 reg µLatory subunit 52 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q07817
Immunogen : Recombinant Human Bcl-2-like protein 1 protein (1-209AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Potent inhibitor of cell death. Inhibits activation of caspases. Appears to reg µLate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1 from the mitochondrial membrane. Also acts as a reg µLator of G2 checkpoint and progression to cytokinesis during mitosis. Ref.17 Ref.19 Ref.20 Isoform Bcl-X(L) also reg µLates presynaptic plasticity, including neurotransmitter release and recovery, number of axonal mitochondria as well as Volume and number of synaptic vesicle clusters. During synaptic stim µLation, increases ATP availability from mitochondria thro µgh reg µLation of mitochondrial membrane ATP synthase F1F0 activity and reg µLates endocytic vesicle retrieval in hippocampal neurons thro µgh association with DMN1L and stim µLation of its GTPase activity in synaptic vesicles.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BCL2L1
Research Areas : Cancer; Cell biology; Metabolism; Signal transduction