BAG3 Antibody HRP conjugated

Volume : 50 µL
Clone Number :
Aliases : BAG 3 antibody; BAG family molec µLar chaperone reg µLator 3 antibody; BAG-3 antibody; Bag3 antibody; BAG3_HUMAN antibody; Bcl 2 binding protein antibody; Bcl-2-associated athanogene 3 antibody; Bcl-2-binding protein Bis antibody; BCL2 associated athanogene 3 antibody; BCL2 binding athanogene 3 antibody; BIS antibody; CAIR 1 antibody; Docking protein CAIR 1 antibody; Docking protein CAIR-1 antibody; MFM6 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O95817
Immunogen : Recombinant Human BAG family molec µLar chaperone reg µLator 3 protein (220-420AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release. Nucleotide release is mediated via its binding to the nucleotide-binding domain (NBD) of HSPA8/HSC70 where as the substrate release is mediated via its binding to the substrate-binding domain (SBD) of HSPA8/HSC70 (PubMed : 9873016, PubMed : 27474739). Has anti-apoptotic activity (PubMed : 10597216). Plays a role in the HSF1 nucleocytoplasmic transport (PubMed : 26159920).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Antigen Affinity purified & Affinity purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BAG3
Research Areas : Signal Transduction