ATF6 Antibody HRP conjugated

Volume : 50 µL
Clone Number :
Aliases : Activating transcription factor 6 alpha antibody; Activating transcription factor 6 antibody; ATF 6 antibody; ATF6 alpha antibody; ATF6 antibody; ATF6-alpha antibody; ATF6A antibody; ATF6A_HUMAN antibody; cAMP dependent transcription factor ATF 6 alpha antibody; cAMP-dependent transcription factor ATF-6 alpha antibody; Cyclic AMP dependent transcription factor ATF 6 alpha antibody; DKFZp686P2194 antibody; ESTM49 antibody; FLJ21663 antibody; Processed cyclic AMP dependent transcription factor ATF 6 alpha antibody; Processed cyclic AMP-dependent transcription factor ATF-6 alpha antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P18850
Immunogen : Recombinant Human Cyclic AMP-dependent transcription factor ATF-6 alpha protein (1-194AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Transmembrane glycoprotein of the endoplasmic retic µLum that functions as a transcription activator and initiates the unfolded protein response (UPR) during endoplasmic retic µLum stress. Cleaved upon ER stress, the N-terminal processed cyclic AMP-dependent transcription factor ATF-6 alpha translocates to the nucleus where it activates transcription of genes involved in the UPR. Binds DNA on the 5\'-CCAC[GA]-3\'half of the ER stress response element (ERSE) (5\'-CCAAT-N(9)-CCAC[GA]-3\') and of ERSE II (5\'-ATTGG-N-CCACG-3\'). Binding to ERSE requires binding of NF-Y to ERSE. Co µLd also be involved in activation of transcription by the serum response factor. May play a role in foveal development and cone function in the retina.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Antigen Affinity purified & Affinity purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ATF6
Research Areas : Signal Transduction